Longevity & Cognition

Sirolimus (Rapamycin)

Starting at$75/ month
Sirolimus (Rapamycin)
Clinician reviewed
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$75.00 per month · 1 mo · 4 Capsule

$75.00

Prescription items are subject to physician review before dispensing. Once you check out, you'll get member portal access to complete a medical intake form. A licensed physician reviews it, and if you're approved, your medication ships. Your provider sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription; if you are not approved, you will not be charged for medication. Compounded formulations are prepared by licensed 503A pharmacies and are not FDA-approved for safety or efficacy. Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects, and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel anytime before renewal at connect@monarchrx.net or +1 979-978-0561.

Understand the protocol

Sirolimus (Rapamycin)

Older man in a blue athletic shirt tying his running shoe outdoors
01What it does

Targets the aging pathway directly.

Sirolimus inhibits mTOR, a key regulator of cellular growth and aging. Low, intermittent dosing promotes autophagy — the cellular cleanup process tied to longevity.

02Who it's for

For dedicated longevity regimens.

Healthy adults pursuing evidence-based longevity intervention, patients focused on healthspan and cellular aging, always under clinician supervision with periodic labs.

03What results look like

A realistic timeline.

Sirolimus isn't a symptom drug — most patients feel nothing acute. Benefits show up through inflammatory markers, metabolic labs and biological age over six to twelve months.

Weeks 1–4
Tolerance check

Weekly dosing begins low. Mouth sores or mild GI upset are the side effects to watch for.

Weeks 4–12
Labs confirm

Follow-up bloodwork checks lipids, glucose and blood counts before the dose is held or adjusted.

Months 3–6
Subjective signal

Recovery, joint comfort and inflammatory markers are the practical read. Benefits here are cumulative, not dramatic.

Years
Long horizon

This is a longevity protocol measured in years, with routine monitoring throughout.

Timelines are typical ranges reported in clinical use and by Monarch Rx patients. Individual results vary with dose, adherence, baseline health and lifestyle.

Labs By Monarch Rx

Brain fog is a symptom.
We find the cause.

Fog has a short list of causes. We check all of them.

01ThyroidWhy thinking feels slow
02Ferritin, B12 & folateWhy you fade by 2pm
03hs-CRP & homocysteineWhy aging speeds up
04Insulin, glucose, HbA1cWhy the brain runs low
05ApoB & lipidsWhy it matters in 20 years
06Vitamin D & CMPWhy your baseline is your baseline