Monarch Rx
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Longevity & Cognition

Metformin XR 500

Starting at$25/ month
Metformin XR 500
Clinician reviewed
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$25.00 per month · 1 mo · 60 Tablet

$25.00

Prescription items are subject to physician review before dispensing. Once you check out, you'll get member portal access to complete a medical intake form. A licensed physician reviews it, and if you're approved, your medication ships. Your provider sets the exact dose during that review.

This is a prescription product and requires an evaluation by a licensed provider. Purchase does not guarantee a prescription; if you are not approved, you will not be charged for medication. Compounded formulations are prepared by licensed 503A pharmacies and are not FDA-approved for safety or efficacy. Availability varies by state. Not for use by anyone under 18. This information is not medical advice — talk to your provider about risks, side effects, and interactions.

Multi-month plans renew automatically at the end of the term until cancelled. Cancel anytime before renewal at connect@monarchrx.net or +1 979-978-0561.

Understand the protocol

Metformin XR 500

Older man in a blue tank top smiling during a workout
01What it does

What Metformin XR 500 does.

Metformin is a well-known oral medication traditionally used to manage type 2 diabetes. In recent years, it has gained recognition in longevity and anti-aging medicine due to its impact on insulin sensitivity, mitochondrial health, inflammation, and cellular aging. As a caloric restriction mimetic, Metformin is now widely used off-label to support metabolic health, fat loss, and cellular resilience, with potential to reduce age-related diseases and improve health span.

02Who it's for

For clinician-directed care.

Metformin XR 500 is prescribed through our Longevity & Cognition program for patients whose intake, symptoms and labs point to a good fit. Your provider confirms it's right for you before anything begins.

03What results look like

A realistic timeline.

Response differs from patient to patient. Your provider tracks symptoms and labs throughout your regimen and adjusts dosing so progress builds steadily rather than all at once.

Weeks 1–2
GI adjustment

Loose stool or bloating is common early with extended-release and usually fades. Take with food.

Weeks 3–8
Glucose steadies

Fasting glucose and post-meal spikes begin to flatten as the dose is titrated.

Months 3–4
Labs confirm

A1c reflects the change at roughly three months — this is the objective checkpoint.

Months 6+
Long-term use

Maintained with periodic B12 and kidney function monitoring.

Timelines are typical ranges reported in clinical use and by Monarch Rx patients. Individual results vary with dose, adherence, baseline health and lifestyle.

Labs By Monarch Rx

Brain fog is a symptom.
We find the cause.

Fog has a short list of causes. We check all of them.

Start Your ProtocolSee The Panel
01ThyroidWhy thinking feels slow
02Ferritin, B12 & folateWhy you fade by 2pm
03hs-CRP & homocysteineWhy aging speeds up
04Insulin, glucose, HbA1cWhy the brain runs low
05ApoB & lipidsWhy it matters in 20 years
06Vitamin D & CMPWhy your baseline is your baseline
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